proteus syndrome: a case report of general and ophthalmic findings

an 18-year-old girl fulfilled the diagnostic criteria for the proteus syndrome (ps). here we report our findings in comprehensive general physical and ocular examination and review the literature focused on clinical manifestations and differential diagnoses. the patient had ‘mild’ involvement of the ophthalmic apparatus: absent foveal reflex, cataract, and abnormal retinal vessels, which in the context of similar reports on ocular manifestations is an indication of wide polymorphism of the condition. dermatologists, geneticists, and ophthalmologists should be aware of this disorder when they are consulted for the diagnosis of hamartomatous dysplasia conditions.   iranian journal of ophthalmology 200921(1):65-69 © 2009 by the iranian society of ophthalmology